Thermo Fisher Scientific Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11), FITC
FITC 형광 표지된 Phospho-CREB (Ser133) 항체로 인간 및 마우스 시료에 반응. Flow Cytometry에 최적화된 재조합 Rabbit Monoclonal 항체. 높은 특이성과 재현성을 제공하며, 4°C 암소 보관 조건. 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CREBS133-4D11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896926 |
Additional Formats
- Unconjugated (MA5-36989)
- APC (MA5-36992)
- PE (MA5-36990)
- Custom conjugation available
Target Information
CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to various extracellular signals such as neurotransmitters, hormones, membrane depolarization, and growth factors. Activation of CREB is dependent upon phosphorylation of serine 133. Phosphorylated CREB functions as an active transcription factor and interacts with CREB binding protein (CBP), a transcriptional coactivator. CREB plays roles in circadian rhythm synchronization, adipocyte differentiation, and learning and memory. In humans, the CREB gene is located on chromosome 2q. Dysfunctions are associated with Alzheimer’s disease, histiocytoma, and soft tissue melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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