Thermo Fisher Scientific Cathelicidin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Cathelicidin antimicrobial peptide. Suitable for WB and IHC applications. Lyophilized form, reconstitutable with distilled water. Provides reliable detection of LL-37/hCAP-18 for innate immunity studies.
- 카탈로그번호
- OSC00028G
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 10–50 µg/mL
- Immunohistochemistry (IHC): 10–50 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Cathelicidin antimicrobial peptide |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11004128 |
Product Specific Information
- Reconstitute with 500 µL of distilled water.
- OSC00028G can be used with blocking peptide GSC00002P.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils. Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in skin.
Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralization, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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