Thermo Fisher Scientific Cathelicidin Polyclonal Antibody
Cathelicidin 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, WB 및 IHC에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 동결건조 형태로 제공됩니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다.
- 카탈로그번호
- OSC00037W
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100 - 1:3000 |
| Immunohistochemistry (IHC) | 1:100 - 1:3000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Cathelicidin antimicrobial peptide |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985793 |
Product Specific Information
Reconstitute with 150 µL of distilled water.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in skin.
Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralization, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment.
Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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