Thermo Fisher Scientific COL9A1 Polyclonal Antibody
COL9A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific COL9A1 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human COL9A1 (Accession P20849), amino acids G424–T474 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852724 |
Product Specific Information
Antibody detects endogenous levels of total Collagen IX alpha 1.
Target Information
COL9A1 encodes one of the three alpha chains of type IX collagen, a minor component (5–20%) of hyaline cartilage. Type IX collagen typically coexists with type II collagen and contributes to the structural integrity of cartilage. Knockout mouse studies show that the alpha 1 chain is essential for assembly of type IX collagen molecules. Deficiency of this protein leads to early-onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis, multiple epiphyseal dysplasia type 6, and Stickler syndrome, which involves ophthalmic, orofacial, articular, and auditory abnormalities.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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