Thermo Fisher Scientific AMZ2 Polyclonal Antibody
Rabbit polyclonal antibody against human AMZ2 protein. Validated for IHC (Paraffin) with dilution 1:50–1:200. Detects endogenous AMZ2 levels. Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human archaelysin family metallopeptidase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635783 |
Product Specific Information
This antibody detects endogenous levels of total AMZ2 protein.
Target Information
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family.
Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis, and also in kidney, liver, pancreas, lung, brain, and placenta.
It is expressed in fetal tissues such as kidney, liver, lung, and brain.
AMZ2 participates in metal ion binding and functions as a zinc metalloprotease.
It is inhibited by general metalloprotease inhibitors o-phenanthroline and batimastat.
Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze Neurogranin or Angiotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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