Thermo Fisher Scientific NOD2 Polyclonal Antibody
인간 NOD2 단백질을 인식하는 Goat Polyclonal 항체로 Western Blot에 적합합니다. CARD15 내부 서열 기반 합성 펩타이드로 면역화되었으며, 0.5 mg/mL 농도의 액상 형태입니다. TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide 포함. -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KFRFTDRERHCSPTD) corresponding to internal amino acids of CARD15 (aa 385–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979202 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
NOD2 is a member of the apoptosis-regulating protein family that includes caspase recruitment domains, Apaf-1, and NOD1. It contains two N-terminal CARDs, a nucleotide-binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs).
NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues).
It plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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