Thermo Fisher Scientific Phospho-MEK7 (Ser271) Polyclonal Antibody
인산화된 MEK7(Ser271)을 특이적으로 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. NIH-3T3 세포 및 인간 뇌 조직 사용 권장. PBS 기반 보관용액에 50% glycerol 포함, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine271 (V-D-S(p)-K-A) derived from Human MAP2K7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554311 |
Product Specific Information
- Suggested positive control for Western blot: NIH-3T3 cells
- Suggested positive control for IHC: Human brain tissue
- Predicted species: Mouse and Rat (100% homology)
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2 and is itself phosphorylated and activated by MAP kinase kinases such as MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK.
This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants exist, but only one variant has been fully defined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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