Thermo Fisher Scientific TIMP2 Monoclonal Antibody (OTI3H8), TrueMAB
TIMP2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot과 유세포분석에 적합합니다. 고순도의 친화 크로마토그래피 정제 제품이며, 동결건조 형태로 제공됩니다. 인간 시료 반응성이 확인된 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H8 |
| Immunogen | Full length human recombinant protein of human TIMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TIMP-1 and TIMP-2 are inhibitors of the matrix metalloproteinase family, essential for maintaining connective tissue integrity.
TIMP-2 binds strongly to both latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2/gelatinase A) and also interacts with active 92 kDa Type IV collagenase (MMP-9/gelatinase B).
TIMP-2 inhibits proteolytic invasiveness of tumor and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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