Thermo Fisher Scientific Human Activin R1B (ALK-4) Fc Chimera Recombinant Protein
CHO 세포에서 발현된 Human Activin R1B (ALK-4) Fc 키메라 재조합 단백질. 웨스턴 블롯, ELISA 등 다양한 분석에 사용 가능. Carrier-free 형태로 제공되어 유연한 실험 조건 설정 가능. 세린/트레오닌 키나아제 신호전달 연구에 적합. 연구용으로만 사용 가능.
- 카탈로그번호
- RP8781x (4개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
4개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Activin R1B (ALK-4) Fc Chimera Recombinant Protein
Applications
Western Blot (WB)
- Assay-dependent
ELISA (ELISA)
- Assay-dependent
Control (Ctrl)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | CHO cells |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Carrier-Free
Stock solutions can also be prepared at 50–100 µg/mL in appropriate sterile buffer.
Carrier protein such as 0.2–1% BSA or HSA can be added when preparing the stock solution.
Target Information
ACVR1B is a serine/threonine kinase involved in signal transduction and cellular communication.
Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors.
Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors.
ACVR1B encodes activin A type IB receptor, composed of 11 exons.
Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants.
The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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