Thermo Fisher Scientific Porcine IL-2, AOF Recombinant Protein

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species

Pig

Expression System

E. coli

Amino acid sequence

MAPTSSSTKN TKKQLEPLLL DLQLLLKEVK NYENADLSRM LTFKFYMPKQ ATELKHLQCL VEELKALEGV LNLGQSKNSD SANIKESMNN INVTVLELKG SETSFKCEYD DETVTAVEFL NKWITFCQSI YSTLT

Molecular weight

15.3 kDa

Class

Recombinant

Type

Protein

Purity

>95% by SDS-Page

Endotoxin concentration

≤1 EU/µg

Activity

ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of CTLL-2 cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.1 mg/mL

Purification

purified

Storage buffer

10mM sodium phosphate, pH 7.5

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Animal Origin Free

Reconstitute with sterile water at 0.1 mg/mL.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.