Thermo Fisher Scientific GI24 (C10orf54) Monoclonal Antibody (OTI6E5), TrueMAB
인간 C10orf54(VISTA) 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합. TrueMAB 형식의 고품질 항체이며, Affinity chromatography로 정제됨. PBS/BSA/glycerol buffer에 보관되며 연구용으로만 사용 가능.
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Thermo Fisher Scientific GI24 (C10orf54) Monoclonal Antibody (OTI6E5), TrueMAB
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E5 |
| Immunogen | Full length human recombinant protein of human C10ORF54 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | 0 |
Target Information
VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1, it has a distinct expression pattern. In both mouse and humans, VISTA is predominantly expressed on hematopoietic cells, with highest densities on myeloid cells and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen-presenting cells directly suppresses proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. Reported ligands of VISTA include CD28H, VSIG-3, and VSIG-8.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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