Thermo Fisher Scientific CNR2 Polyclonal Antibody
Human CB2 수용체를 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. Affinity chromatography로 정제되었으며, PBS/BSA/glycerol buffer에 보관. 다양한 종에 반응하며 연구용으로 적합.
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Thermo Fisher Scientific CNR2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250–1:2500 | View 4 publications |
| Immunohistochemistry (IHC) | - | View 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | View 3 publications |
| Flow Cytometry (Flow) | 1:50 | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Hamster, Horse, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein containing the first 33 amino acid residues from human CB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2082910 |
Product Specific Information
PA1-744 detects cannabinoid receptor 2 (CB2) from human tissues.
It has been successfully used in Western blot, FACS, immunocytochemistry, and immunofluorescence procedures.
By Western blot, this antibody detects an ~60 kDa band from human spinal cord homogenate and a ~40 kDa band from RBL2H3 cells, representing the different glycosylated forms of CB2.
The antigen is a fusion protein containing the first 33 amino acid residues from human CB2.
Target Information
Cannabinoids exert their physiological effects through two G protein-coupled receptors: cannabinoid receptor 1 (CB1) and CB2.
Both receptors inhibit adenylyl cyclase and stimulate MAPK signaling.
CB1 receptors also modulate ion channels through direct G-protein interactions.
Delta 9-tetrahydrocannabinol and related ligands exert psychoactive effects by inhibiting presynaptic calcium channels.
CB2 is primarily involved in immune system function and may also be present in the central nervous system, including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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