Thermo Fisher Scientific APC13 Polyclonal Antibody
Thermo Fisher Scientific의 APC13 폴리클로날 항체는 인간 및 생쥐에 반응하며, 세포주기 관련 단백질 ANAPC13을 검출합니다. Western blot에 적합하며 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ANAPC13 (Accession Q9BS18), corresponding to amino acid residues I15–L65 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850242 |
Product Specific Information
Antibody detects endogenous levels of total ANAPC13.
Target Information
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is essential for normal mitosis progression.
APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase controlling progression through mitosis and G1 phase.
APC/C degrades anaphase inhibitors, mitotic cyclins, and spindle-associated proteins to ensure proper mitotic sequence.
APC13 promotes stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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