Thermo Fisher Scientific PEX5 Monoclonal Antibody (OTI6C4), TrueMAB
PEX5 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합. 인간 PEX5 전장 재조합 단백질을 면역원으로 제작. 고순도 친화 크로마토그래피 정제, 무보존제 PBS 버퍼에 동결건조 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C4 |
| Immunogen | Full length human recombinant protein of human PEX5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
Peroxins (PEXs) are required for assembly of functional peroxisomes.
Defects in PEX5 are associated with peroxisome biogenesis disorders (PBDs), including neonatal adrenoleukodystrophy (NALD), Zellweger syndrome (ZWS), and infantile Refsum disease (IRD).
Alternative splicing results in different isoforms of the protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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