Thermo Fisher Scientific H3K18cr Polyclonal Antibody
H3K18cr 변형을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. ICC/IF, ELISA, ChIP 등 다양한 연구용 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 기반 용액 형태로 -20°C 또는 -80°C 보관합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:200
ELISA
- Tested Dilution: Assay-dependent
ChIP assay
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of Crotonyl-Lys (18) derived from Human Histone H3.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3091422 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. It is located separately from other H3 genes in the histone gene cluster on chromosome 6p22-p21.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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