Thermo Fisher Scientific PTPN11 Monoclonal Antibody (OTI2F4), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting.
(Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)

Target Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that function as phospho-tyrosine binding domains and mediate substrate interactions.
It is widely expressed in most tissues and plays a regulatory role in cell signaling events important for mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.