Thermo Fisher Scientific H4K20me1 Monoclonal Antibody (3E7D9)
H4K20me1 단일클론 항체(3E7D9)는 인간 히스톤 H4의 메틸화된 리신 20을 인식합니다. IHC, ICC/IF, ELISA에 적합하며, 단백질 G로 정제된 액상 항체입니다. 단기 4°C, 장기 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E7D9 |
| Immunogen | Synthesized peptide of human HIST2H4A (AA: GGAKRHRK(Me)VLRDNIQ) (aa 14–28) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787386 |
Product Specific Information
MA5-31763 has been tested in indirect ELISA.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped to form nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, contributing to chromatin compaction into higher-order structures.
The HIST2H4A gene encodes a member of the histone H4 family, is intronless, and lacks a polyA tail, instead containing a palindromic termination element. It is located within the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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