Thermo Fisher Scientific RSPO4 Monoclonal Antibody (435203)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

435203

Immunogen

E. coli-derived recombinant mouse R-Spondin 4 Tyr21-Pro197 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RSPO4,uniProtId:Q8BJ73-1,ncbiNodeId:10090,antigenRange:21-197,antigenLength:228,antigenImageFileName:MA5-24160_RSPO4_Q8BJ73-1_Rat.svg,antigenImageFileNamePDP:MA5-24160_RSPO4_Q8BJ73-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606925

Product Specific Information

In Western blots, 50-100% cross-reactivity with recombinant human (rh) R-Spondin 4 is observed and no cross-reactivity with recombinant mouse (rm) R-Spondin 1, rmR-Spondin 3, or rhR-Spondin 2 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.