Thermo Fisher Scientific PDZD2 Polyclonal Antibody
Human PDZD2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 단기 4°C, 장기 -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA564169
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDZD2. Recombinant protein control fragment (Product # RP-103558) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645363 |
Product Specific Information
Immunogen sequence:
LMVGVDVSGA SYLAEQCWNG GFIYLIMLRR FKHKAHSTYN GNSSNSSEPG ETPTLELGDR TAKKGKRTRK FGVISRPPAN KAPEESKGS
- Highest antigen sequence identity to orthologs:
- Mouse: 88%
- Rat: 84%
Target Information
Proteins containing PDZ domains often bind to the C-termini of transmembrane receptors or ion channels. They may also interact with other PDZ domain proteins and participate in intracellular signaling.
The PDZD2 gene encodes a protein with six PDZ domains, showing sequence similarity to pro-interleukin-16 (pro-IL-16). Like pro-IL-16, it localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains.
This gene is upregulated in primary prostate tumors and may play a role in early prostate tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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