Thermo Fisher Scientific MPP5 Monoclonal Antibody (OTI5D10), TrueMAB

Applications

• Western Blot (WB): 1:500–1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

MPP5 (Membrane Protein, Palmitoylated 5) plays a key role in neurogenesis and hematopoiesis, crucial for maintaining cell polarity in epithelial cells and neurons.
It participates in the Par-3 complex, supporting tight junction integrity.
Mutations in MPP5 are linked to global developmental delay (GDD) and behavioral abnormalities.
In animal models, MPP5 influences early progenitor differentiation and contributes to myeloid and lymphoid lineages.
Variants can disrupt normal cellular function, leading to developmental and functional defects.

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.