Thermo Fisher Scientific MPP5 Monoclonal Antibody (OTI5D10), TrueMAB
인간 MPP5 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, PBS와 trehalose 버퍼에 보존됩니다. 세포 극성 유지 및 신경 발생 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D10 |
| Immunogen | Full-length human recombinant MPP5 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MPP5 (Membrane Protein, Palmitoylated 5) plays a key role in neurogenesis and hematopoiesis, crucial for maintaining cell polarity in epithelial cells and neurons.
It participates in the Par-3 complex, supporting tight junction integrity.
Mutations in MPP5 are linked to global developmental delay (GDD) and behavioral abnormalities.
In animal models, MPP5 influences early progenitor differentiation and contributes to myeloid and lymphoid lineages.
Variants can disrupt normal cellular function, leading to developmental and functional defects.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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