Thermo Fisher Scientific SLC29A3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SLC29A3 protein. Suitable for ICC/IF applications with 0.25–2 µg/mL dilution. Antigen affinity purified, supplied in PBS with glycerol and sodium azide. For research use only.
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- PA565424
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SLC29A3 (Recombinant protein control fragment, Product #RP-95808) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2664675 |
Product Specific Information
- Immunogen sequence:
YARYYMRPVLA AHVFSGEEEL PQDSLSAPSV ASRFIDSHTP PLRPILKKT - Antigen sequence identity:
Mouse 64%, Rat 62%
Target Information
SLC29A3 is a member of the equilibrative nucleoside transporter family, essential for nucleoside and nucleobase uptake in nucleotide salvage pathways.
This transmembrane glycoprotein localizes to the lysosomal membrane and functions as a broad selectivity, low affinity nucleoside transporter.
Mutations in SLC29A3 are linked to H syndrome, characterized by cutaneous hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism.
A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), is also associated with mutations at this locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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