Thermo Fisher Scientific GM-CSF Monoclonal Antibody (A6C5)
Thermo Fisher Scientific GM-CSF Monoclonal Antibody (A6C5)은 인간 GM-CSF를 인식하는 Mouse IgG1 항체로, WB 및 ELISA에 적합합니다. 고순도 Protein G 정제, 2 mg/mL 농도, 안정적 PBS 기반 저장용액. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| ELISA | 1:30,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6C5 |
| Immunogen | Recombinant protein within Human GM-CSF aa 1–144/144 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091037 |
Product Specific Information
- Predicted band size: 16 kDa
- Subcellular Location: Secreted
- Product MA5-50584 was used in an Indirect ELISA.
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space.
This gene is located in a cluster of related genes at chromosome region 5q31, associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia.
Other genes in this cluster include interleukins 4, 5, and 13. The gene promotes tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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