Thermo Fisher Scientific Syntenin 1 Polyclonal Antibody
Syntenin 1 단백질을 표적하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 인간에 반응하며 개, 생쥐, 랫드에서도 예측 반응합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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- PA518595
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.01–0.03 µg/mL | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SLEDLKVDKVIQAQ) corresponding to the N-terminus amino acids of SDCBP (aa 6–20) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985187 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton.
Syntenin protein contains tandemly repeated PDZ domains that bind cytoplasmic, C-terminal domains of various transmembrane proteins.
It may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and transcription factor activation.
Primarily localized to membrane-associated adherens junctions and focal adhesions, also found in the endoplasmic reticulum and nucleus.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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