Thermo Fisher Scientific FEZ2 Polyclonal Antibody
FEZ2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, Rat 반응성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–500 |
| Immunocytochemistry (ICC/IF) | 1:50–500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Fasciculation And Elongation Protein Zeta 2 (FEZ2). The antigen corresponds to amino acid range 1–375 of the target protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903605 |
Target Information
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues.
FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner.
FEZ2 can interact with FEZ1 through its C-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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