Thermo Fisher Scientific MYO1A Polyclonal Antibody
MYO1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 반응합니다. Western blot에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 보관하며, -20°C에서 안정적으로 저장 가능합니다.
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- pk
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human MYO1A (UniProt ID: Q9UBC5-1, amino acids 405–433) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691956 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The MYO1A gene encodes a member of the myosin superfamily, which functions as molecular motors interacting with actin filaments to generate mechanical force via ATP hydrolysis.
Each myosin includes:
- A conserved N-terminal motor domain with ATP- and actin-binding sites
- A light-chain-binding neck region containing IQ motifs for calmodulin binding
- A C-terminal tail domain involved in dimerization, membrane binding, and protein interactions
In kidney epithelial cells (LLC-PK1-CL4), MYO1A localizes to the brush border, where its head and tail domains interact with actin and the plasma membrane, respectively. The protein exhibits rapid turnover compared to the static actin core structure.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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