Thermo Fisher Scientific ZHX2 Polyclonal Antibody
Thermo Fisher Scientific의 ZHX2 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 항체입니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, KLH 접합 합성 펩타이드(aa 451–550)를 면역원으로 사용했습니다. Protein A로 정제된 액상 형태로 -20°C에 보관합니다.
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Thermo Fisher Scientific ZHX2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ZHX2 (amino acids 451–550) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA).
ZHX1–3 are ubiquitously expressed transcriptional repressors localized in the nucleus.
They contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), enabling both homodimer and heterodimer formation.
Dimerization is not required for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event associated with hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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