Thermo Fisher Scientific Human ERR Gamma, Ligand Binding Domain, GST Tag Recombinant Protein

Applications

Tested Dilution

Publications

Ligand Binding Assay (LBA)

Assay-dependent

-

Product Specifications

Species

Human

Expression System

Baculovirus

Amino acid sequence

229-458

Tag

GST-tag

Class

Recombinant

Type

Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

purified

Storage buffer

proprietary buffer

Contains

no preservative

Storage conditions

-80° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Product Specific Information

ESRRG (estrogen-related receptor gamma) ligand binding domain is a 54.05 kDa recombinant human protein (amino acids 229-458) expressed as a GST-tagged fusion protein in baculovirus-infected insect cells. ERR γ-LBD is expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

Protein Form: Recombinant, Ligand Binding Domain

Target Information

Estrogen-related receptor gamma (ERRG, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. ERRG acts as a transcription activator in the absence of a bound ligand. It binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. ERRG also induces the expression of PERM1 in the skeletal muscle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.