
Thermo Fisher Scientific TMEM27 Polyclonal Antibody
Human TMEM27 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 베타 세포 증식 관련 연구 및 TMEM27 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TMEM27. Recombinant protein control fragment (Product #RP-91896) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648687 |
Product Specific Information
Immunogen sequence:
LVTAIHAELC QPGAENAFKV RLSIRTALGD KAYAWDTNEE YLFKAMVAFS MRKVPNREAT EISHVLLCNV TQRVSFWFVV TDPSKNHTLP AVEVQSAIRM NKNRINNAFF LNDQTLE
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 87%
Target Information
TMEM27 (Transmembrane protein 27), also known as collectrin, belongs to the TMEM27 family. It stimulates beta cell replication and serves as a membrane protein cleaved and shed by pancreatic beta cells, proposed as a beta cell mass biomarker.
Western blot analysis of mouse collecting duct cell lines detected TMEM27 at an apparent molecular mass of 32 kDa. TMEM27 is an N-glycosylated protein and forms dimers with a molecular weight of 64–75 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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