Thermo Fisher Scientific Human MORF4 Synthetic Peptide
인간 MORF4 단백질의 N-말단 18개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20399의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2) 내 0.1% BSA 포함, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP0516
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human MORF4.
PEP-0516 can be used as a blocking peptide with polyclonal antibody PA5-20399.
Target Information
Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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