
Thermo Fisher Scientific KLRD1 Monoclonal Antibody (OTI8E10), TrueMAB
인간 KLRD1(CD94)을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 최적화되어 있습니다. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용하며, 동결건조 형태로 제공됩니다. 연구용으로 NK 세포 관련 연구에 적합합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–179 + Mouse FC of human KLRD1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Natural killer (NK) cells, including CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation.
Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may regulate NK cell function.
KLRD1 (CD94) is preferentially expressed on NK cells and classified as a type II membrane protein with an external C terminus.
Three transcript variants encoding two different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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