
Thermo Fisher Scientific DTX4 Polyclonal Antibody
Human DTX4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. Notch signaling 관련 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DTX4. Recombinant protein control fragment (Product #RP-101733) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640817 |
Product Specific Information
Immunogen sequence:
TSPPMSPCSC PQCVLVMSVK AAVVNGSTGP LQLPVTRKNM PPPGVVKLP
Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 73%
Target Information
DTX4 is a regulator of Notch signaling, a pathway involved in cell-cell communication and regulation of diverse cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating Lys48-linked polyubiquitination and promoting degradation of TBK1. Targeting to TBK1 requires interaction with NLRP4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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