Thermo Fisher Scientific PAIP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PAIP2. Recombinant protein control fragment (Product #RP-103268). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PAIP2,uniProtId:Q9BPZ3-1,ncbiNodeId:9606,antigenRange:2-35,antigenLength:127,antigenImageFileName:PA5-63347_PAIP2_Q9BPZ3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63347_PAIP2_Q9BPZ3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645179

Product Specific Information

Immunogen sequence: KDPSRSSTSP SIINEDVIIN GHSHEDDNPF AEYM

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Target Information

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.