Thermo Fisher Scientific MTCH2 Polyclonal Antibody
MTCH2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 세포자멸사 경로 연구용으로 적합. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human MTCH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155449 |
Product Specific Information
- A suggested positive control is 293 cell lysate.
- PA5-20696 can be used with blocking peptide PEP-0811.
Target Information
MTCH2 is a member of the mitochondrial carrier protein family that catalyzes the exchange of substrates across the inner mitochondrial membrane. It is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in various diseases such as cancer.
The Bcl-2 family of proteins includes critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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