Thermo Fisher Scientific AMPK beta-2 Polyclonal Antibody
AMPK beta-2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. IHC, ICC/IF, Flow Cytometry에 사용 가능하며, 고순도 액상 형태로 제공. 세포 에너지 대사 연구용으로 적합.
- 카탈로그번호
- PA5142354
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PYGQEMYAFRSE (AMPK beta-2, UniProt ID: O43741-1, antigen range: 188–199, antigen length: 272) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933004 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits.
It functions as an important energy-sensing enzyme that monitors cellular energy status.
In response to metabolic stress, AMPK becomes activated and phosphorylates key enzymes such as acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), regulating fatty acid and cholesterol biosynthesis.
The beta-2 subunit may act as a positive regulator of AMPK activity and serve as an adaptor mediating complex assembly.
Myristoylation and phosphorylation of this subunit influence enzyme activity and subcellular localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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