Thermo Fisher Scientific MTHFR Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662870

Product Specific Information

Immunogen sequence: GYHSLRQLVKL SKLEVPQEIK DVIEPIKDND AAIRNYGIEL AVSLCQELLA SGLVPGLHFY TLNREMATTE VLKRLGMWTE DPRRPLPWAL SAHPKRREED VRPIFWASRP KSYIYRTQEW DEFPNGRWGN SSSPA

Highest antigen sequence identity to the following orthologs - mouse 94%, rat 93%.

Target Information

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.