Thermo Fisher Scientific CD13 Monoclonal Antibody (TUK 1), Alexa Fluor 488

Applications

• Flow Cytometry (Flow): Assay-dependent

Product Specifications

Additional Formats

• APC ([MHCD1305])
• FITC ([MHCD1301])
• PE ([MHCD1304])
• Custom conjugation available

Product Specific Information

Based on testing, publications, and customer reports, Alexa Fluor™ 488 dye provides the best fluorescein (FITC) substitute for this antibody.

Target Information

CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It acts as a metalloprotease that removes neutral amino acids from small peptides, modulating bioactive peptide activity. CD13 plays roles in extracellular matrix degradation, antigen processing, and signal transduction, contributing to inflammatory responses, intercellular contact regulation, cell motility, and vascularization. It is expressed by granulocytes, monocytes, and myeloid leukemia cells, associated with poor carcinoma prognosis and protection of leukemic cells against apoptosis. CD13 functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.

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