
Thermo Fisher Scientific CD13 Monoclonal Antibody (TUK 1), TRI-COLOR
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Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
Assay-Dependent
Product Specifications
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
TUK 1
Immunogen
Human CD13
Conjugate
TRI-COLOR™ TRI-COLOR™ TRI-COLOR™
View additional formats
Excitation/Emission Max
567/671 nm View spectra
Form
Liquid
Storage conditions
4° C, store in dark
Shipping conditions
Wet ice
RRID
AB_10373534
Product Specific Information
The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5 conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
Target Information
CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
Analyte Specific Reagent
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