Thermo Fisher Scientific NPTX2 Polyclonal Antibody
NPTX2 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human NPTX2 (amino acids 165–265) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neuronal pentraxin (NPTX) 2 is a member of the pentraxin family with high homology to NPTX1. Unlike NPTX1, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle, and brain. It exhibits lectin properties, promotes neurite outgrowth, and is regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes contributing to excitatory synaptogenesis. NPTX2 is upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and neurites, suggesting involvement in Parkinson’s disease-related dysregulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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