Thermo Fisher Scientific APOBEC3G Polyclonal Antibody
APOBEC3G 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도, 인간 시료 반응성. 연구용으로만 사용 가능.
- 카탈로그번호
- BS-15407R
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific APOBEC3G Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human APOBEC3G, amino acids 201–300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Apoliprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) 3 family consists of cytidine deaminases acting on monomeric nucleoside and nucleotide substrates. APOBEC3G, a key isoform, contributes to cellular defense against retroviral infection by incorporating into HIV-1 virions and inducing hypermutation in viral DNA, thereby destabilizing the viral genome. This mechanism is counteracted by the HIV-1 Vif protein, which promotes ubiquitination and degradation of APOBEC3G. A single amino acid substitution (D128K) blocks APOBEC3G depletion while maintaining its antiviral activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.