Thermo Fisher Scientific PSMB4 Polyclonal Antibody
Thermo Fisher Scientific의 PSMB4 Polyclonal Antibody는 인간 PSMB4 단백질을 인식하는 토끼 다클론 항체로, WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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- PA552328
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMB4. Recombinant protein control fragment (Product #RP-89179) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646062 |
Product Specific Information
Immunogen sequence:
VIDEELLGDG HSYSPRAIHS WLTRAMYSRR SKMNPLWNTM VIGGYADGES FLGYVDMLGV AYEAPSLATG YGAYLAQPLL REVLEKQPVL SQTEARDLVE RCMRVLYYRD ARSYNRFQIA TVTEKGVEIE GPLSTETNWD IA
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 96%
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of four rings of 28 non-identical subunits; two rings are composed of seven alpha subunits and two rings are composed of seven beta subunits. Proteasomes are distributed throughout eukaryotic cells at high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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