Thermo Fisher Scientific PDCL3 Monoclonal Antibody (OTI8D6), TrueMAB
PDCL3 단백질을 인식하는 단일클론 항체로 Western blot에 최적화됨. 인간, 마우스, 랫트 반응성. 무보존제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- CF809677
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D6 |
| Immunogen | Full length human recombinant protein of human PDCL3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains, initially identified as modulators of G protein signaling.
PDCL3 is highly homologous to PDCL and contains an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain.
Together with PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding.
MAPK phosphorylation and RhoA-dependent changes in PDCL3 levels promote cytoskeletal remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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