Thermo Fisher Scientific ATG9A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 10–50 µg/mL

Immunohistochemistry (IHC)

• Tested Dilution: 10–50 µg/mL

Product Specifications

Product Specific Information

• Reconstitute with 500 µL of distilled water.
• Centrifuge to remove any insoluble material.

Target Information

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells. It is responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.
Macroautophagy involves the formation of double-membrane bound autophagosomes that enclose cytoplasmic constituents targeted for degradation, which then fuse with lysosomes (or vacuoles), releasing single-membrane bound autophagic bodies that are degraded within these organelles.
Apg9 plays a direct role in the formation of cytoplasm-to-vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.