Thermo Fisher Scientific Phospho-HRH1 (Ser398) Polyclonal Antibody
인간, 생쥐, 랫트 반응성을 가진 HRH1 Ser398 인산화 부위 특이적 항체. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-HRH1 (Ser398) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human HRH1 around phosphorylation site Ser398 [SH(p-S)RQ] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its actions are mediated by histamine receptors H1, H2, H3, and H4.
The HRH1 gene encodes an integral membrane protein belonging to the G protein-coupled receptor superfamily. It mediates smooth muscle contraction, increases capillary permeability, stimulates catecholamine release from the adrenal medulla, and facilitates neurotransmission in the central nervous system.
Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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