Thermo Fisher Scientific PF4 Polyclonal Antibody
PF4 단백질에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 ELISA에 사용 가능. 인간 반응성, E. coli 유래 재조합 단백질 면역원 사용. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human PF4 recombinant protein (Position: E32–S101) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746924 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Platelet factor-4 (PF4) is a 70-amino acid protein released from the alpha-granules of activated platelets. It binds with high affinity to heparin, neutralizing heparin-like molecules on endothelial surfaces, thereby inhibiting local antithrombin III activity and promoting coagulation. PF4 also acts as a chemoattractant for neutrophils and fibroblasts, suggesting a role in inflammation and wound repair (Eisman et al., 1990).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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