Thermo Fisher Scientific IL6ST/CD130 Polyclonal Antibody
IL6ST/CD130 단백항체는 사람과 생쥐 반응성을 가지며, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합형 액상 항체로, IL-6 수용체 복합체 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 868 to 918 of human Interleukin-6 receptor subunit beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM).
This protein functions as a part of the cytokine receptor complex. Activation of this protein depends on cytokine binding to their receptors.
vIL6, encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the IL6 receptor (IL6R) and directly activate this protein.
Knockout studies in mice suggest a critical role in regulating myocyte apoptosis.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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