Thermo Fisher Scientific IL6ST/CD130 Polyclonal Antibody
IL6ST/CD130 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 IL6 수용체 서브유닛 베타 영역(868-918)을 면역원으로 사용하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 868 to 918 of human Interleukin-6 receptor subunit beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
The protein encoded by this gene is a signal transducer shared by multiple cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). It functions as part of the cytokine receptor complex, and activation depends on cytokine binding to their receptors.
vIL6, encoded by Kaposi sarcoma-associated herpesvirus, can bypass IL6R and directly activate this protein. Knockout studies in mice suggest a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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