
Thermo Fisher Scientific CENPJ Monoclonal Antibody (5D5)
Thermo Fisher Scientific의 CENPJ 단클론 항체(5D5)는 인간 단백질을 인식하는 Mouse IgG2a 항체로, Western blot과 ELISA에 적합합니다. 액상 형태로 보존제가 없으며 -20°C에서 보관합니다. 세포 분열 및 중심체 연구용으로 적합한 연구용 시약입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D5 |
| Immunogen | CENPJ (NP_060921, 979–1088 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KYTTAARTFP DKKEREEIQT LKQQIADLRE DLKRKETKWS STHSRLRSQI QMLVRENTDL REEIKVMERF RLDAWKRAEA IESSLEVEKK DKLANTSVRF QNSQISSGTQ
Target Information
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome.
It can also function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with the coactivator p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by reduced brain size and mental retardation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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