Thermo Fisher Scientific Relaxin 1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

In direct ELISAs, less than 1% cross-reactivity with recombinant human Relaxin-1 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Target Information

Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In humans, there are three non-allelic relaxin genes: RLN1, RLN2, and RLN3. RLN1 and RLN2 share high sequence homology.

The encoded protein is synthesized as a single-chain polypeptide; the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary and acts on the reproductive system to ripen the cervix, elongate the pubic symphysis, and inhibit uterine contraction. It may also play roles in sperm motility, blood pressure regulation, heart rate control, and hormone release (oxytocin and vasopressin).

This gene has multiple polyadenylation sites and several alternatively spliced transcript variants, though their full-length nature is not yet fully characterized.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.