Thermo Fisher Scientific Relaxin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Relaxin 1 Polyclonal Antibody는 마우스 Relaxin-1 단백질을 특이적으로 인식하는 항체입니다. Western blot 및 IHC(Frozen)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA547858
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse Relaxin-1 Arg23–Arg54 with an N-terminal Met (B chain) and Glu161–Cys185 (A chain) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608719 |
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human Relaxin-1 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In humans, there are three non-allelic relaxin genes: RLN1, RLN2, and RLN3. RLN1 and RLN2 share high sequence homology.
The encoded protein is synthesized as a single-chain polypeptide; the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary and acts on the reproductive system to ripen the cervix, elongate the pubic symphysis, and inhibit uterine contraction. It may also play roles in sperm motility, blood pressure regulation, heart rate control, and hormone release (oxytocin and vasopressin).
This gene has multiple polyadenylation sites and several alternatively spliced transcript variants, though their full-length nature is not yet fully characterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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