Thermo Fisher Scientific GNB1 Polyclonal Antibody
GNB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, IP에 사용 가능. 인간, 마우스, 랫트 반응성 확인. 고순도 항원 친화 크로마토그래피 정제, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA530046
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 67–271 of Human GNB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.44 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2547520 |
Product Specific Information
- Recommended positive controls: Jurkat, Raji, NCI-H929, Mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (96%), Dog (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%), Guinea pig (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Vision involves the conversion of light into electrochemical signals processed by the retina and transmitted to the brain. Rhodopsin, a membrane-bound protein, absorbs light and activates transducin, a GTP-binding protein. Activated transducin promotes cGMP hydrolysis by phosphodiesterase (PDE), leading to closure of ion channels and membrane hyperpolarization. Rhodopsin activity is terminated by phosphorylation and arrestin binding. Transducin composition differs between photoreceptor cells—rod transducin (Trα, Tβ, Tγ) and cone transducin (Tcα, Tβ, Tγ)—which contributes to varying light sensitivities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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