Thermo Fisher Scientific MEK2 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 MAPK/ERK kinase 2 (MEK2) 타겟 인식. Western blot, IHC, IP 등 다양한 응용 가능. 액상 형태, 4°C 보관, 1년의 권장 보관기간. Mouse 및 Dog에 교차 반응 예측.
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Thermo Fisher Scientific MEK2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human MAPK/ERK kinase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Dog
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase involved in mitogen growth factor signal transduction. MEK2 (MAPKK2) activates ERK1/2 and MAPK by phosphorylating residues within the TEY motif in the activation loop. MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, providing negative feedback regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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